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新闻动态
中药生产工艺的设计
(1)工艺确定之后,装备是为工艺服务的。即一个产品工艺确定以后,制约它的第一个因素就是装备,没有制药装备去为工艺服务,生产的药品也达不到要求。另外,由于目前一些大型中药企业,关键设备大多为国外引进的设备,但国外设备不一定完全适用于中药生产,故中药装备还是要结合中药自身的特点进行自行开发和深化设计,要吸收懂制药工艺的人员或与业主负责工艺的相关人员一起进行再次设计和开发,只有这样,才能使开发的产品发挥它的效能,满足生产工艺的需要。
(1) after the process is determined, the equipment is provided for the process. That is, after a product process is determined, the first factor restricting it is equipment. Without pharmaceutical equipment to serve the process, the drugs produced can not meet the requirements. In addition, because most of the key equipments in some large-scale Chinese medicine enterprises are imported from abroad, but the foreign equipments are not necessarily suitable for the production of Chinese medicine. Therefore, Chinese medicine equipments should be self-developed and designed according to the characteristics of Chinese medicine itself, and should absorb the personnel who understand the pharmaceutical technology or be responsible for the process with the owner. Customs personnel work together to redesign and develop. Only in this way can the developed products give full play to their effectiveness and meet the needs of production technology.
(2)在进行深化工艺设计过程中,要本着“最好的就是最适用的”的设计指导思想以及充分体现内部设计人性化、设备自动化、管理数字化、标准国际化的设计理念进行深化设计,充分考虑到业主的实际工艺生产的需要、工艺和能量平衡,以及维护成本、可预见的市场需求增加扩容的灵活性、投资预算等,以达到“性价比” 最优。
(2) In the process of deepening process design, we should deepen the design in line with the design guiding ideology of "the best is the most suitable" and fully embody the design concepts of humanization of internal design, automation of equipment, digitalization of management and internationalization of standards, fully taking into account the actual process production needs and processes of the owners. And energy balance, as well as maintenance costs, predictable market demand increase flexibility, investment budget, etc., in order to achieve "cost-effective" optimal.
(3)考虑中药现代化程度较高中药厂项目的关键设备一般为国外成套引进,且初步工艺设计是由国外工程公司依据国际医药行业通用标准进行设计,虽然整线的初步工艺设计思想和理念是先进的,但仍需要根据中国GMP要求、业主的实际情况和工程施工实际情况进行深化工艺设计和自控设计,确保工艺单元分配合理、布置紧凑、自动化程度满足需要,使其控制系统能完全实现各单元的工艺设计要求,且将第三方设备合理的、低成本的接入全厂的自动控制系统。因药厂具有工艺过程复杂、工艺单元较多以及医药行业生产过程的无菌要求,因此应确保控制系统具有完善的安全联锁控制、实时操作、工艺参数整定、配方批次管理、报表分析,历史记录等功能。
(3) Considering that the key equipment of the project of Chinese traditional medicine factory with higher modernization degree is generally imported from abroad, and the preliminary process design is designed by foreign engineering companies according to the general standards of international pharmaceutical industry. Although the preliminary process design ideas and concepts of the whole line are advanced, it still needs to be in accordance with the requirements and industries of China's GMP. The actual situation of the main project and the actual construction situation deepen the process design and automatic control design to ensure that the process unit distribution is reasonable, the layout is compact and the degree of automation meets the needs, so that the control system can fully realize the process design requirements of each unit, and the third-party equipment will be reasonable and low-cost automatic access to the whole plant. Control system. Pharmaceutical factories have complex process, more process units and aseptic requirements of pharmaceutical industry production process. Therefore, it is necessary to ensure that the control system has perfect functions such as safety interlocking control, real-time operation, parameter setting, batch management of formulation, report form analysis, historical record and so on.

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