联系我们

公司名称:XXX

电话:XXX

手机:XXX

联系人:XXX

地址:XXX

新闻动态
中药有效成分辨识

中药复方的药效物质基础是一个比较笼统的概念,从“宏观到微观”或者“自上而下”,可以分为4个层次:有效药材(饮片)、有效部位、有效组分(群)、有效成分(群)。虽然各个层次之问不能完全等同,但是宏观层次的药效活性,必然是微观层次各种化学成分交互作用“涌现”的结果,因此,从根本上讲,饮片层次上的临床疗效必然是有效成分综合作用的结果。
The efficacy of compound material basis of TCM, which is a more general concept, from macroscopic to microcosmic "or" top-down ", can be divided into four levels: effective herbs (slices), effective part and effective components (group), effective component (group). Although not completely equal, the question of all levels but the efficacy of the macro level activity, is necessarily the micro level of various chemical interaction "emergent" as a result, therefore, fundamentally, the clinical curative effect of yinpian level must be a result of the combined action of active ingredients.
面对通过临床实践及数据挖掘技术所确定中药新药研发的处方,如何辨识有效成分是中药新药研究不可回避的关键科学问题之一。就目前状况而言,从中药中发现高活性单体化合物的难度越来越大,而且这种研究方法与中医理论严重脱节,无法回归到中医。中医历来强调药物之间的配伍,“七情合和”是中医组方的基本原则,认为“药有个性之特长,方有合群之妙用”。即使是单味药,治疗某一病症时,也往往多成分综合效应。如银杏叶国际通用标准提取物(EGb761)的成功开发等大量的中药研究实践告诉我们,片面追求中药及其复方中单一化学成分的研究之路,越来越窄;重视多种成分的综合效应,探讨多成分组合的药理效应规律,是符合中药自身作用特点的研究方法。
Face through clinical practice and data mining technology to determine the research and development of new drug of TCM prescription, how to identify effective component is the research of new drug of TCM is one of the key scientific problems. In terms of the situation, from the difficulty of the highly reactive monomer compounds found in traditional Chinese medicine is more and more big, and the research method and the theory of traditional Chinese medicine the disconnect, unable to return to the traditional Chinese medicine. Has always stressed used in traditional Chinese medicine, the compatibility between the and "seven emotions" is the basic principle of TCM formula, think "medicine has the specialty of personality, are" really low on agreeableness of use ". Even when it comes to a single dose of medicine, it is often a combination of multiple components. Such as ginkgo biloba Ye Guoji universal standard extract (EGb761) the successful development of a large number of traditional Chinese medicine research practice tells us that the one-sided pursuit of traditional Chinese medicine and its way to the study of the single chemical composition of the compound, more and more narrow; It is the research method that accords with the characteristics of Chinese traditional Chinese medicine.

联系方式

  1. 公司名称:XXX
  2. 电话:XXX
  3. 手机:XXX
  4. 联系人:XXX
  5. 地址:XXX

版权 © 安国中药柜生产厂  网址:zhongyaogui.71ix.com 推荐:实木中药柜,不锈钢中药柜,中药设计制作

网站建设及优化保定遨游网络公司